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細(xì)胞衰老抑制基因抗體
  • 產(chǎn)品貨號：
    BN41805R
  • 中文名稱：
    細(xì)胞衰老抑制基因抗體
  • 英文名稱：
    Rabbit anti-RSL1D1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價(jià)

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  • BN41805R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Mouse,Rat 推薦應(yīng)用：WB,IHC-P

  • BN41805R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse,Rat 推薦應(yīng)用：WB,IHC-P

  • BN41805R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse,Rat 推薦應(yīng)用：WB,IHC-P

產(chǎn)品描述

英文名稱RSL1D1
中文名稱細(xì)胞衰老抑制基因抗體
別    名CATX 11; CATX-11; CATX11; Cellular senescence inhibited gene protein; L12; PBK1; CSIG; L12; PBK1; Protein PBK1; Ribosomal L1 domain-containing protein 1; RL1D1_HUMAN; Ribosomal L1 domain containing 1.  
研究領(lǐng)域腫瘤  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat, 
產(chǎn)品應(yīng)用WB=1:500-2000 IHC-P=1:400-800 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量55kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse RSL1D1:311-410/452 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹RSL1D1, also known as CATX-11, PBK1, L12 or CSIG, is a 490 amino acid nuclear protein that belongs to the ribosomal protein L1P family. Expressed in placenta, RSL1D1 contains many phosphorylated amino acid residues and is encoded by a gene that maps to human chromosome 16p13.13. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias.

Subcellular Location:
Nucleus, nucleolus.

Tissue Specificity:
Placenta.

Similarity:
Belongs to the ribosomal protein L1P family. Highly divergent.

SWISS:
Q8BVY0

Gene ID:
66409

Database links:

Entrez Gene: 26156 Human

SwissProt: O76021 Human

Unigene: 401842 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CSIG可抑制細(xì)胞衰老并延長細(xì)胞壽命 ,可能通過核糖體生物合成過程或基因轉(zhuǎn)錄調(diào)節(jié)來調(diào)控細(xì)胞衰老過程.