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單核細(xì)胞趨化誘導(dǎo)蛋白1抗體
  • 產(chǎn)品貨號(hào)：
    BN41924R
  • 中文名稱：
    單核細(xì)胞趨化誘導(dǎo)蛋白1抗體
  • 英文名稱：
    Rabbit anti-MCPIP1 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41924R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IF,Flow-Cyt,ELISA

  • BN41924R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IF,Flow-Cyt,ELISA

  • BN41924R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱MCPIP1
中文名稱單核細(xì)胞趨化誘導(dǎo)蛋白1抗體
別    名dJ423B22.1; MCP 1 treatment-induced protein; MCP-induced protein 1; MCPIP 1; MCPIP; Ribonuclease ZC3H12A; RP3-423B22.1; ZC12A_HUMAN; ZC3H 12A; ZC3H12 A; Zc3h12a; Zinc finger CCCH domain-containing protein 12A; Zinc finger CCCH type containing 12A.  
研究領(lǐng)域腫瘤  心血管  細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量66kDa
細(xì)胞定位細(xì)胞核 細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MCPIP1:201-300/599 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.

Function:
Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the ZC3H12 family.
Contains 1 C3H1-type zinc finger.

SWISS:
Q5D1E8

Gene ID:
80149

Database links:

Entrez Gene: 535344 Cow

Entrez Gene: 80149 Human

Entrez Gene: 230738 Mouse

Omim: 610562 Human

SwissProt: A6QQJ8 Cow

SwissProt: Q5D1E8 Human

SwissProt: Q5D1E7 Mouse

Unigene: 656294 Human

Unigene: 402 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications