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首頁>>免疫學(xué)>>一抗>>鈉碘單獨(dú)轉(zhuǎn)運(yùn)蛋白SLC26A4抗體
鈉碘單獨(dú)轉(zhuǎn)運(yùn)蛋白SLC26A4抗體
  • 產(chǎn)品貨號(hào)：
    BN41951R
  • 中文名稱：
    鈉碘單獨(dú)轉(zhuǎn)運(yùn)蛋白SLC26A4抗體
  • 英文名稱：
    Rabbit anti-SLC26A4 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號(hào)

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  • BN41951R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA

  • BN41951R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱SLC26A4
中文名稱鈉碘單獨(dú)轉(zhuǎn)運(yùn)蛋白SLC26A4抗體
別    名PDS; deafness, autosomal recessive 4; DFNB4; EVA; NSRD4; Pendred syndrome; Pendred syndrome homolog; Pendrin; S26A4_HUMAN; SLC26A4; Sodium independent chloride/iodide transporter; Sodium-independent chloride/iodide transporter; Solute carrier family 26 member 4.  


研究領(lǐng)域細(xì)胞  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 Flow-Cyt=1ug/test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量93kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Solute carrier family 26 member 4:301-400/780 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Several alternatively spliced transcript variants of this gene, encoding distinct isoforms, have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

Function:
Sodium-independent transporter of chloride and iodide.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues.

DISEASE:
Defects in SLC26A4 are the cause of deafness autosomal recessive type 4 (DFNB4) [MIM:600791]; also known as vestibular aqueduct syndrome (EVA). DFNB4 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNB4 is associated with an enlarged vestibular aqueduct.

Similarity:
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. Contains 1 STAS domain.

SWISS:
O43511

Gene ID:
5172

Database links:
UniProtKB/Swiss-Prot: O43511.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















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